How things are done, processes, the building blocks of business are changing.  You build successful organizations by building processes(sets of activities and decisions to achieve specific goals)  but now it's even more important that you optimize the people, technology and analytics in these processes if you want a successful result (and more literally, if you want to survive).  This is increasingly complicated by the fact that many processes, especially those involving the product or service delivery cycle, involve and flow through multiple organizations.